幸运勋章怎么获得得 camouflaged 勋章

Access denied | www.voltairenet.org used Cloudflare to restrict access
Please enable cookies.
What happened?
The owner of this website (www.voltairenet.org) has banned your access based on your browser's signature (3bf48bdab5d276ee-ua98).博狗集团是不是骗人的热新闻
澎湃新闻APP下载
博狗集团是不是骗人的热门推荐当前位置:
Pub Date&:&
Shi-Ying Li, Hong Cheng, Bo-Ru Xie, Wen-Xiu Qiu, Jing-Yue Zeng, Chu-Xin Li, Shuang-Shuang Wan, Lu Zhang, Wen-Long Liu, Xian-Zheng Zhang
Selectively cuting off the nutrient supply and the metabolism pathways of cancer cells would be a promising approach to improve the efficiency of cancer treatment. Here, a cancer targeted cascade bioreactor (designated as mCGP) was constructed for synergistic starvation and photodynamic therapy (PDT) by embedding glucose oxidase (GOx) and catalase in the cancer cell membrane-camouflaged porphyrin metal–organic framework (MOF) of PCN-224 (PCN stands for porous coordination network). Due to biomimetic surface functionalization, the immune escape and homotypic targeting behaviors of mCGP would dramatically enhance its cancer targeting and retention abilities. Once internalized by cancer cells, mCGP was found to promote microenvironmental oxygenation by catalyzing the endogenous hydrogen peroxide (H2O2) to produce oxygen (O2), which would subsequently accelerate the decomposition of intracellular glucose and enhance the production of cytotoxic singlet oxygen (1O2) under light irradiation. Consequently, mCGP displayed amplified synergistic therapeutic effects of long-term cancer starvation therapy and robust PDT, which would efficiently inhibit the cancer growth after a single administration. This cascade bioreactor would further facilitate the development of complementary modes for spatiotemporally controlled cancer treatment.
更新日期:
Some contents have been Reproduced with permission of the American Chemical Society.Some contents have been Reproduced by permission of The Royal Society of Chemistry.

我要回帖

更多关于 dnf完美勋章怎么获得 的文章

 

随机推荐